Job Details
A post-doctoral fellow position is immediately available in Dr. Karen Bussard’s laboratory within the Department of Cancer Biology at Thomas Jefferson University, Sidney Kimmel Cancer Center, located in downtown Philadelphia. Dr. Bussard is looking for a highly motivated post-doctoral fellow interested in cancer metastasis to the bone and the tumor microenvironment. The laboratory utilizes murine models of metastasis, human patient samples, primary cell culture, molecular biology techniques, high-end fluorescence microscopy, biomedical engineering, and 3-D models to answer questions related to molecular and cellular aspects of bone metastatic breast cancer.
Recent work in the laboratory has identified a subpopulation of osteoblasts in the bone-tumor microenvironment that play a role in tumor progression. We are interested both in how this osteoblast subpopulation affects metastatic breast cancer cells as well as how these cells interact with the surrounding bone stroma during disease progression.
Job Description
Requirements:
Candidates must have a Ph.D. in cancer biology, cell biology, molecular biology, or a closely related field. Candidates should also have authored at least one first author publication (either published or in revision) in reputable journals. Candidates will be working with cell-based models of cancer and murine models of cancer metastasis. Must be proficient in mouse handling/ experimentation, models of cancer, and performing molecular biology techniques including cloning/ plasmid manipulation, transfection, knock-in/knock-out experiments, real-time PCR, RT-PCR, immunoblotting, ELISA, microarray analysis, IHC/IF, standard cell culture, and fluorescence & confocal microscopy. Experience with 3D models of cell culture, exosomes, and/or a bioengineering background are also desirable.
Candidates should have excellent oral and written communication skills, highly developed interpersonal skills, and display initiative as well as independence.
Interested individuals must be authorized to work in the United States and should submit their CV (with publications as appropriate), a letter of interest, and the names and contact information of three (3) references to Dr. Karen Bussard (karen.bussard@jefferson.edu).
Work Shift
Workday Day (United States of America)
Worker Sub Type
Regular
Primary Location Address
951 Locust Street, Philadelphia, Pennsylvania, United States of America
Nationally ranked, Jefferson, which is principally located in the greater Philadelphia region, Lehigh Valley and Northeastern Pennsylvania and southern New Jersey, is reimagining health care and higher education to create unparalleled value. Jefferson is more than 65,000 people strong, dedicated to providing the highest-quality, compassionate clinical care for patients; making our communities healthier and stronger; preparing tomorrow's professional leaders for 21st-century careers; and creating new knowledge through basic/programmatic, clinical and applied research. Thomas Jefferson University, home of Sidney Kimmel Medical College, Jefferson College of Nursing, and the Kanbar College of Design, Engineering and Commerce, dates back to 1824 and today comprises 10 colleges and three schools offering 200+ undergraduate and graduate programs to more than 8,300 students. Jefferson Health, nationally ranked as one of the top 15 not-for-profit health care systems in the country and the largest provider in the Philadelphia and Lehigh Valley areas, serves patients through millions of encounters each year at 32 hospitals campuses and more than 700 outpatient and urgent care locations throughout the region. Jefferson Health Plans is a not-for-profit managed health care organization providing a broad range of health coverage options in Pennsylvania and New Jersey for more than 35 years.
Jefferson is committed to providing equal educational and employment opportunities for all persons without regard to age, race, color, religion, creed, sexual orientation, gender, gender identity, marital status, pregnancy, national origin, ancestry, citizenship, military status, veteran status, handicap or disability or any other protected group or status.