Are you looking to contribute to groundbreaking research? This is a great opportunity for you!
Cedars-Sinai is an international leader in biomedical research, we translate discoveries into successful treatments with global impact.
Principal Investigator, Dr. Richard Ainsworth, PhD is looking for a Postdoctoral Scientist to join his dynamic team!
The primary focus of the Ainsworth lab is the development of integrative systems biology methods for multi-omics data. The lab has specific interests in transcriptional dysregulation and aberrant signaling in autoimmune disorders, such as Rheumatoid Arthritis, Scleroderma, and Lupus, and we are working to gain new insights into disease mechanisms.
About the Role
We are looking for a driven individual who has expertise in innate immune signaling and/or immunometabolism who is interested in translating their knowledge to help better understand the immunopathology of Lupus. Using mouse models or primary human patient specimens our goals are to understand how RNA/DNA sensing pathways and the proteins that regulate them contribute to Lupus pathology. Secondly, we are interested in determining how immunometabolic reprogramming contributes to epigenetic changes in Lupus immune cells and how we can use this knowledge to restore immune homeostasis. Focus will be on using next-generation sequencing, proteomics and advanced imaging to address each of these questions.
Working independently but in close collaboration and in consultation with the Principal Investigator and other Research Scientist, the Postdoctoral Scientist will perform routine and sophisticated laboratory procedures throughout this training period. The incumbent may develop, adapt, and implement new research techniques and protocols.
Primary Duties and Responsibilities:
- May assist in preparation of grant proposals but is not responsible for generating grant funds.
- May participate in publications and presentations as author or co-author.
- Designs and performs experiments.
- Will keep appropriate experimental records and documentation and analyze the results.
- Analyzes, interprets, summarizes, and compiles data.
- Operates and maintains equipment and instruments.
Education:
Doctorate (MD, PhD, VMD, or DDS) in area related to field of research specialization.
Experience:
- Works independently on research projects designed by a mentor (typically the PI) within area of specialization.
- Applicants will ideally have a strong expertise in cellular and molecular immunology with an interest in the role of RNA/DNA sensors or immunometabolism in driving inflammation.
- Proficiency in data analysis approaches using Python or R is desirable.
- Demonstrated aptitude to apply molecular biology and cell biology techniques to solve complex questions and become proficient in and apply new technologies to these questions as required.
- Acquires complete technical and theoretical knowledge of research project and objectives during one to five (1-5) year post-doctoral appointment.
Cedars-Sinai is a leader in providing high-quality healthcare encompassing primary care, specialized medicine and research. Since 1902, Cedars-Sinai has evolved to meet the needs of one of the most diverse regions in the nation, setting standards in quality and innovative patient care, research, teaching and community service. Today, Cedars- Sinai is known for its national leadership in transforming healthcare for the benefit of patients. Cedars-Sinai impacts the future of healthcare by developing new approaches to treatment and educating tomorrow's health professionals. Additionally, Cedars-Sinai demonstrates a commitment to the community through programs that improve the health of its most vulnerable residents.
Cedars-Sinai is one of the largest nonprofit academic medical centers in the U.S., with 886 licensed beds, 2,100 physicians, 2,800 nurses and thousands of other healthcare professionals and staff. Choose this if you want to work in a fast-paced environment that offers the highest level of care to people in the Los Angeles that need our care the most.
Req ID : 12185
Working Title : Postdoctoral Scientist - Division of Rheumatology / Department of Medicine
Department : Research - Rheumatology
Business Entity : Cedars-Sinai Medical Center
Job Category : Academic / Research
Job Specialty : Postdoctoral Scholar
Overtime Status : EXEMPT
Primary Shift : Day
Shift Duration : 8 hour
Base Pay : $62,400.00 - $93,600.00
